Lung Intelligence for COVID-19

Quantitative Precision

VIDA Insights provides quantitative measures and distribution of ground glass/reticulation, consolidation and honeycombing.

An overlay of these findings is also provided together with hyperlucent tissue, indicative of emphysema.

Published works are indicating a primary imaging feature of COVID-19 to include ground-glass opacities with or without consolidation.^2,3

Quantitative lung consolidation is associated with the occurrence of major adverse hospital events for COVID-19 patients.⁴

Comorbid Assessment

VIDA Insights also provides density analysis and tMPR visualizations.

Comorbid Assessment of underlying conditions, such as COPD, are key to understanding the increased vulnerability of disease progression with COVID-19 and/or complications associated with recovery. VIDA Insights provides:

Low attenuation (LAA%), a validated surrogate measure of emphysema. COVID-19 patients with COPD have a significantly higher risk of progression and readmission.^5-7
Well-aerated lung (normal density) - lung parenchyma was found to be a strong predictor of intensive care unit (ICU) admission or death.⁸

VIDA Insights is clinically cleared in the US, EU, Australia & Canada. Texture and Subpleura View are available in the US and Canada under the public health emergency and available for research use in the EU and Australia.

References

1 -Wang, Bolin, Ruobao Li, Zhong Lu, and Yan Huang. “Does Comorbidity Increase the Risk of Patients with COVID-19: Evidence from Meta-Analysis.” Aging 12 (April 8, 2020). https://doi.org/10.18632/aging.103000.
2 - Colombi et al “Well-Aerated Lung on Admitting Chest CT to Predict Adverse Outcome in COVID-19 Pneumonia.” Radiology, April 17, 2020, 201433. https://doi.org/10.1148/radiol.2020201433.
3. Wang, Bolin, et al. “Does Comorbidity Increase the Risk of Patients with COVID-19: Evidence from Meta- Analysis.” Aging, vol. 12, Apr. 2020. PubMed, doi:10.18632/aging.103000
4- Sapienza, Lucas G., Karim Nasra, Vinícius F. Calsavara, Tania B. Little, Vrinda Narayana, and Eyad Abu-Isa. “Risk of In-Hospital Death Associated with Covid-19 Lung Consolidations on Chest Computed Tomography – A Novel Translational Approach Using a Radiation Oncology Contour Software.” European Journal of Radiology Open 8 (January 1, 2021): 100322. https://doi.org/10.1016/j.ejro.2021.100322.
5 - Schroeder J, et al. Relationships between airflow obstruction and quantitative CT measurements of emphysema, air trapping and airways in subjects with and without chronic obstructive pulmonary disease. AM J Roentgenol. 2013 Sept; 201(3).
6. Zach J, et al. Quantitative CT of the lungs and airways in healthy non-smoking adults. Invest. Radiology. 2012 Oct; 47(10).
7. Lowe K, et al. COPDGene 2019: Redefining the diagnosis of Chronic Obstructive Pulmonary Disease. JOPDF. 2019 Nov; 6(5)
8. Colombi et al “Well-Aerated Lung on Admitting Chest CT to Predict Adverse Outcome in COVID-19 Pneumonia.” Radiology, April 17, 2020, 201433. https://doi.org/10.1148/radiol.2020201433