Conclusions
Fibrotic changes occured in more than one-third of patients who survived severe COVID-19 pneumonia.
These changes were associated with an older age, acute respiratory distress syndrome, longer in-hospital stays, tachycardia, non-invasive mechanical ventilation and higher initial chest CT score.
Significance
Many patients who survive severe COVID-19 experience long term lung damage that must be managed. This study showed that more than 1/3 of severe patients are left with fibrotic disease 6 months after their COVID-19 infection. Measuring recovery quantitatively with HAA and texture analysis provides an objective assessment; novel visualizations like tMPR and subpleura view give providers a impactful view of longitudinal changes that can be especially helpful in collaborative discussions with members of the care team and the patient.
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