COPD

Select peer-reviewed papers:
COPD & VIDA’s quantitative CT (QCT) analysis.

1.
Woodruff, P. G. et al. Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function. New England Journal of Medicine 374, 1811–1821 (2016).
1.
Wang, J. M., Ram, S., Labaki, W. W., Han, M. K. & Galbán, C. J. CT-Based Commercial Software Applications: Improving Patient Care Through Accurate COPD Subtyping. Int J Chron Obstruct Pulmon Dis 17, 919–930 (2022).
1.
Motahari, A. et al. Repeatability of Pulmonary Quantitative CT Measurements in COPD. Am J Respir Crit Care Med rccm.202209-1698PP (2023) http://doi.org/10.1164/rccm.202209-1698PP.
1.
Ritchie, A. I. et al. Structural Predictors of Lung Function Decline in Young Smokers with Normal Spirometry (BEACON). Am J Respir Crit Care Med (2024) http://doi.org/10.1164/rccm.202307-1203OC.
1.
Sharma, M., Kirby, M., McCormack, D. G. & Parraga, G. Machine Learning and CT Texture Features in Ex-smokers with no CT Evidence of Emphysema and Mildly Abnormal Diffusing Capacity. Academic Radiology 0, (2023).
1.
Armstrong, H. F. et al. Lung function, percent emphysema, and QT duration: The Multi-Ethnic Study of Atherosclerosis (MESA) lung study. Respir Med 123, 1–7 (2017).
1.
Beiko, T. et al. Serum Proteins Associated with Emphysema Progression in Severe Alpha-1 Antitrypsin Deficiency. Chronic Obstr Pulm Dis 4, 204–216 (2017).
1.
Choi, S. et al. Differentiation of quantitative CT imaging phenotypes in asthma versus COPD. BMJ Open Respiratory Research 4, e000252 (2017).
1.
Cosentino, J. et al. Analysis of Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome Defined on the Basis of Bronchodilator Response and Degree of Emphysema. Ann Am Thorac Soc 13, 1483–1489 (2016).
1.
Smith, B. M. et al. Human airway branch variation and chronic obstructive pulmonary disease. Proceedings of the National Academy of Sciences 115, E974–E981 (2018).
1.
Washko, G. R., Coxson, H. O., O'Donnell, D. E. & Aaron, S. D. CT imaging of chronic obstructive pulmonary disease: insights, disappointments, and promise. The Lancet Respiratory Medicine 5, 903–908 (2017).
1.
Gompelmann, D. et al. The minimal important difference for target lobe volume reduction after endoscopic valve therapy. Int J Chron Obstruct Pulmon Dis 13, 465–472 (2018).
1.
Yablonskiy, D. A. Air Trapping - Insights from CT and In Vivo Lung Morphometry with Hyperpolarized 3He MRI. American Thoracic Society International Conference Meetings Abstracts American Thoracic Society International Conference Meetings Abstracts.
1.
Lo Cascio, C. M. et al. Percent Emphysema and Daily Motor Activity Levels in the General Population. Chest 151, 1039–1050 (2017).
1.
Oelsner, E. C. et al. Association between emphysema-like lung on cardiac computed tomography and mortality in persons without airflow obstruction: a cohort study. Ann Intern Med 161, 863–873 (2014).
1.
Smith, B. M. et al. Not all measures of hyperinflation are created equal: lung structure and clinical correlates of gas trapping and hyperexpansion in COPD: the Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study. Chest 145, 1305–1315 (2014).
1.
Martinez, C. H. et al. Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS. Am J Respir Crit Care Med 195, 464–472 (2017).
1.
Newell, J. D., Sieren, J. & Hoffman, E. A. Development of quantitative computed tomography lung protocols. J Thorac Imaging 28, 266–271 (2013).
1.
Han, M. K. et al. Prevalence and clinical correlates of bronchoreversibility in severe emphysema. Eur Respir J 35, 1048–1056 (2010).
1.
Martinez, F. J. et al. Sex differences in severe pulmonary emphysema. AM.REV.RESPIR.DIS. 176, 243–252 (2007).
1.
Burkart, K. M. et al. APOM and High-Density Lipoprotein are associated with Lung Function and Percent Emphysema. Eur Respir J 43, 1003–1017 (2014).
1.
Powell, R. et al. Genetic ancestry and the relationship of cigarette smoking to lung function and per cent emphysema in four race/ethnic groups: a cross-sectional study. Thorax 68, 634–642 (2013).
1.
Barr, R. G. et al. Percent Emphysema, Airflow Obstruction, and Impaired Left Ventricular Filling. N Engl J Med 362, 217–227 (2010).
1.
Krachman, S. L. et al. Effect of Emphysema Severity on the Apnea-Hypopnea Index in Smokers with Obstructive Sleep Apnea. Ann Am Thorac Soc 13, 1129–1135 (2016).
1.
Xu, Y., Sonka, M., McLennan, G., Guo, J. & Hoffman, E. A. MDCT-based 3-D texture classification of emphysema and early smoking related lung pathologies. IEEE Trans Med Imaging 25, 464–475 (2006).
1.
Zach, J. A. et al. Quantitative computed tomography of the lungs and airways in healthy nonsmoking adults. Invest Radiol 47, 596–602 (2012).
1.
Sieren, J. P. et al. Reference standard and statistical model for intersite and temporal comparisons of CT attenuation in a multicenter quantitative lung study. Med Phys 39, 5757–5767 (2012).
1.
Putman, R. K. et al. Association Between Interstitial Lung Abnormalities and All-Cause Mortality. JAMA 315, 672–681 (2016).
1.
Iyer, K. S., Grout, R. W., Zamba, G. K. & Hoffman, E. A. Repeatability and Sample Size Assessment Associated with Computed Tomography-Based Lung Density Metrics. Chronic Obstr Pulm Dis 1, 97–104 (2014).
1.
Chen-Mayer, H. H. et al. Standardizing CT lung density measure across scanner manufacturers. Med Phys 44, 974–985 (2017).