Emphysema

Select peer-reviewed papers:
Emphysema & VIDA’s quantitative CT (QCT) analysis.

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Woodruff, P. G. et al. Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function. New England Journal of Medicine 374, 1811–1821 (2016).
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Armstrong, H. F. et al. Lung function, percent emphysema, and QT duration: The Multi-Ethnic Study of Atherosclerosis (MESA) lung study. Respir Med 123, 1–7 (2017).
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Beiko, T. et al. Serum Proteins Associated with Emphysema Progression in Severe Alpha-1 Antitrypsin Deficiency. Chronic Obstr Pulm Dis 4, 204–216 (2017).
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Choi, S. et al. Differentiation of quantitative CT imaging phenotypes in asthma versus COPD. BMJ Open Respiratory Research 4, e000252 (2017).
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Herth, F. J. F. et al. The Modern Art of Reading Computed Tomography Images of the Lungs: Quantitative CT. Respiration 95, 8–17 (2018).
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Smith, B. M. et al. Human airway branch variation and chronic obstructive pulmonary disease. Proceedings of the National Academy of Sciences 115, E974–E981 (2018).
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Washko, G. R., Coxson, H. O., O'Donnell, D. E. & Aaron, S. D. CT imaging of chronic obstructive pulmonary disease: insights, disappointments, and promise. The Lancet Respiratory Medicine 5, 903–908 (2017).
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Valipour, A. et al. Endobronchial Valve Therapy in Patients with Homogeneous Emphysema. Results from the IMPACT Study. Am J Respir Crit Care Med 194, 1073–1082 (2016).
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Gompelmann, D. et al. The minimal important difference for target lobe volume reduction after endoscopic valve therapy. Int J Chron Obstruct Pulmon Dis 13, 465–472 (2018).
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Khauli, S., Bolukbas, S., Reed, R. M. & Eberlein, M. Interlobar collateral ventilation in severe emphysema. Thorax 71, 1168–1169 (2016).
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Yablonskiy, D. A. Air Trapping - Insights from CT and In Vivo Lung Morphometry with Hyperpolarized 3He MRI. American Thoracic Society International Conference Meetings Abstracts American Thoracic Society International Conference Meetings Abstracts.
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Valipour, A. et al. Patterns of Emphysema Heterogeneity. Respiration 90, 402–411 (2015).
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de Oliveira, H. G., de Oliveira, S. M., Rambo, R. R. & de Macedo Neto, A. V. Fissure Integrity and Volume Reduction in Emphysema: A Retrospective Study. Respiration 91, 471–479 (2016).
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Barjaktarevic, I. et al. Diffusing capacity for carbon monoxide correlates best with tissue volume from quantitative CT scanning analysis. Chest 147, 1485–1493 (2015).
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Lo Cascio, C. M. et al. Percent Emphysema and Daily Motor Activity Levels in the General Population. Chest 151, 1039–1050 (2017).
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Oelsner, E. C. et al. Per cent emphysema is associated with respiratory and lung cancer mortality in the general population: a cohort study. Thorax 71, 624–632 (2016).
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Oelsner, E. C. et al. Association between emphysema-like lung on cardiac computed tomography and mortality in persons without airflow obstruction: a cohort study. Ann Intern Med 161, 863–873 (2014).
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Smith, B. M. et al. Not all measures of hyperinflation are created equal: lung structure and clinical correlates of gas trapping and hyperexpansion in COPD: the Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study. Chest 145, 1305–1315 (2014).
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Martinez, C. H. et al. Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS. Am J Respir Crit Care Med 195, 464–472 (2017).
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Newell, J. D., Sieren, J. & Hoffman, E. A. Development of quantitative computed tomography lung protocols. J Thorac Imaging 28, 266–271 (2013).
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Han, M. K. et al. Prevalence and clinical correlates of bronchoreversibility in severe emphysema. Eur Respir J 35, 1048–1056 (2010).
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Martinez, F. J. et al. Sex differences in severe pulmonary emphysema. AM.REV.RESPIR.DIS. 176, 243–252 (2007).
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Burkart, K. M. et al. APOM and High-Density Lipoprotein are associated with Lung Function and Percent Emphysema. Eur Respir J 43, 1003–1017 (2014).
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Powell, R. et al. Genetic ancestry and the relationship of cigarette smoking to lung function and per cent emphysema in four race/ethnic groups: a cross-sectional study. Thorax 68, 634–642 (2013).
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Lovasi, G. S. et al. Socioeconomic status is positively associated with percent emphysema on CT scan: The MESA lung study. Acad Radiol 18, 199–204 (2011).
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Barr, R. G. et al. Percent Emphysema, Airflow Obstruction, and Impaired Left Ventricular Filling. N Engl J Med 362, 217–227 (2010).
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Martinez, F. J. et al. Predictors of Mortality in Patients with Emphysema and Severe Airflow Obstruction. Am J Respir Crit Care Med 173, 1326–1334 (2006).
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Krachman, S. L. et al. Effect of Emphysema Severity on the Apnea-Hypopnea Index in Smokers with Obstructive Sleep Apnea. Ann Am Thorac Soc 13, 1129–1135 (2016).
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Uppaluri, R., Mitsa, T., Hoffman, E. A., McLennan, G. & Sonka, M. Texture analysis of pulmonary parenchyma in normal and emphysematous lung. 2709, 456–467 (1996).
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Uppaluri, R. et al. Computer recognition of regional lung disease patterns. Am J Respir Crit Care Med 160, 648–654 (1999).
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Xu, Y., Sonka, M., McLennan, G., Guo, J. & Hoffman, E. A. MDCT-based 3-D texture classification of emphysema and early smoking related lung pathologies. IEEE Trans Med Imaging 25, 464–475 (2006).
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Uppaluri, R., Mitsa, T., Sonka, M., Hoffman, E. A. & McLennan, G. Quantification of pulmonary emphysema from lung computed tomography images. Am J Respir Crit Care Med 156, 248–254 (1997).
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Elbehairy, A. F. et al. Pulmonary Vascular Volume by Quantitative CT in Dyspneic Smokers with Minor Emphysema. COPD: Journal of Chronic Obstructive Pulmonary Disease 20, 135–143 (2023).